Physical activity boosts the immune system. This is dependent on the concentration of endogenous factors (such as sex hormones, metabolic hormones and growth hormones), body temperature, blood flow, hydration status and body position.[37] Physical activity has shown to increase the levels of natural killer (NK) cells, NK T cells, macrophages, neutrophils and eosinophils, complements, cytokines, antibodies and T cytotoxic cells.[38][39] However, the mechanism linking physical activity to immune system is not fully understood. 

Centers for disease control and prevention provide lifestyle guidelines of maintaining a balanced diet and engaging in physical activity to reduce the risk of disease. The WCRF/ American Institute for Cancer Research (AICR) published a list of recommendations that reflect the evidence they have found through consistency in fitness and dietary factors that directly relate to cancer prevention.
These recommendations are also widely supported by the American Cancer Society. The guidelines have been evaluated and individuals that have higher guideline adherence scores substantially reduce cancer risk as well as help towards control with a multitude of chronic health problems. Regular physical activity is a factor that helps reduce an individual’s blood pressure and improves cholesterol levels, two key components that correlate with heart disease and Type 2 Diabetes.[33] The American Cancer Society encourages the public to "adopt a physically active lifestyle" by meeting the criteria in a variety of physical activities such as hiking, swimming, circuit training, resistance training, lifting, etc. It is understood that cancer is not a disease that can be cured by physical fitness alone, however, because it is a multifactorial disease, physical fitness is a controllable prevention. The large associations tied with being physically fit and reduced cancer risk are enough to provide a strategy to reduce cancer risk.[32] The American Cancer Society asserts different levels of activity ranging from moderate to vigorous to clarify the recommended time spent on a physical activity. These classifications of physical activity consider the intentional exercise and basic activities are done on a daily basis and give the public a greater understanding of what fitness levels suffice as future disease prevention.
Fitness is defined as the quality or state of being fit.[5] Around 1950, perhaps consistent with the Industrial Revolution and the treatise of World War II, the term "fitness" increased in western vernacular by a factor of ten.[6] The modern definition of fitness describes either a person or machine's ability to perform a specific function or a holistic definition of human adaptability to cope with various situations. This has led to an interrelation of human fitness and attractiveness that has mobilized global fitness and fitness equipment industries. Regarding specific function, fitness is attributed to persons who possess significant aerobic or anaerobic ability, i.e. endurance or strength. A well-rounded fitness program improves a person in all aspects of fitness compared to practicing only one, such as only cardio/respiratory endurance or only weight training.

These types include cardiorespiratory endurance, which is how long or fast a person can perform an activity and how this impacts heart rate and oxygen consumption. Muscular strength, which is how much weight can be moved in relation to repetitions and muscular power, which is how much force can be generated during a given activity. There is also flexibility, how far a muscle group can be stretched or joint can be moved. Balance how long a particular position can be held with or without some type of activity being performed. Speed, how quickly an individual can move from one point to another. And body composition, the amount of fat on the body versus other tissues such as muscle, bones and skin.

These recommendations are also widely supported by the American Cancer Society. The guidelines have been evaluated and individuals that have higher guideline adherence scores substantially reduce cancer risk as well as help towards control with a multitude of chronic health problems. Regular physical activity is a factor that helps reduce an individual’s blood pressure and improves cholesterol levels, two key components that correlate with heart disease and Type 2 Diabetes.[33] The American Cancer Society encourages the public to "adopt a physically active lifestyle" by meeting the criteria in a variety of physical activities such as hiking, swimming, circuit training, resistance training, lifting, etc. It is understood that cancer is not a disease that can be cured by physical fitness alone, however, because it is a multifactorial disease, physical fitness is a controllable prevention. The large associations tied with being physically fit and reduced cancer risk are enough to provide a strategy to reduce cancer risk.[32] The American Cancer Society asserts different levels of activity ranging from moderate to vigorous to clarify the recommended time spent on a physical activity. These classifications of physical activity consider the intentional exercise and basic activities are done on a daily basis and give the public a greater understanding of what fitness levels suffice as future disease prevention.
A comprehensive fitness program tailored to an individual typically focuses on one or more specific skills,[7] and on age-[8] or health-related needs such as bone health.[9] Many sources[10] also cite mental, social and emotional health as an important part of overall fitness. This is often presented in textbooks as a triangle made up of three points, which represent physical, emotional, and mental fitness. Physical fitness can also prevent or treat many chronic health conditions brought on by unhealthy lifestyle or aging.[11] Working out can also help some people sleep better and possibly alleviate some mood disorders in certain individuals.[12]
The US guidelines continue: For additional and more extensive health benefits, adults should increase their aerobic physical activity to 300 minutes (5 hours) a week of moderate-intensity, or 150 minutes a week of vigorous-intensity aerobic physical activity, or an equivalent combination of moderate- and vigorous-intensity activity. Additional health benefits are gained by engaging in physical activity beyond this amount. Adults should also do muscle-strengthening activities that are moderate or high intensity and involve all major muscle groups on 2 or more days a week, as these activities provide additional health benefits.[14]
Studies have revealed that this type of physical fitness training is more efficient in burning calories over a shorter period than steady-state activity or performing the exercise routine repeatedly. Another benefit of this training is that it enables an individual to develop his or her routine by mixing and matching his or her choice of activities or exercises. Different mixes and matches can produce different results.
Endurance is your ability to perform physical activity over time. You might be able to serve aces and hit winning forehands and backhands, but if your muscles cramp or you run out of energy after a few games, you won’t win any matches. You build endurance by exercising for longer periods without stopping, working at a slower speed than when you interval train. This type of exercise is usually aerobic, calling on your slow-twitch muscle fibers and burning more fat than glycogen, depending on the speed you work. The slower you work, the higher percentage of your calories burned comes from fat.
To exercise, work, do daily chores and play sports, you’ll need varying levels of cardiorespiratory capacity and stamina, muscle strength and endurance, footwork skills and speed. Training for one type of fitness often requires different types of exercises than training for another type of fitness. For example, strength training uses heavy weights and slower muscle movements than sprint training, which is performed with little resistance and high-speed muscle movements. These different types of fitness workouts recruit different muscle fibers and burn different amounts of fat and glycogen. It's best to focus on strength and endurance exercise during a sport off-season, and work on speed and recovery during the preseason and in season.
The US guidelines continue: For additional and more extensive health benefits, adults should increase their aerobic physical activity to 300 minutes (5 hours) a week of moderate-intensity, or 150 minutes a week of vigorous-intensity aerobic physical activity, or an equivalent combination of moderate- and vigorous-intensity activity. Additional health benefits are gained by engaging in physical activity beyond this amount. Adults should also do muscle-strengthening activities that are moderate or high intensity and involve all major muscle groups on 2 or more days a week, as these activities provide additional health benefits.[14]

People who are physically fit are also healthier, are able to maintain their most optimum weight, and are also not prone to cardiac and other health problems. In order to maintain a relaxed state of mind, a person should be physically active. A person who is fit both physically and mentally is strong enough to face the ups and downs of life, and is not affected by drastic changes if they take place.

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